Clinical Uses of Lactate and Lactate Clearance in Carbon Monoxide Poisoning

Acute Carbon Monoxide Poisoning in a Poisoning Referral Center

Bachground: Acute carbon monoxide poisoning (COP) is a common problem that occurs more frequently during winter and leads to serious complications. In our Poisoning Referral Center, the incidence and complications of acute COP has not been evaluated previously. Therefore we designed a study to evaluate its significance in our center. Methods & Materials: 111 cases of acute COP admitted duri...

"Lactate Shift," Rather Than "Lactate Clearance," for Serial Blood Lactate Monitoring?

Mass carbon monoxide poisoning.

The largest occurrence of carbon monoxide poisoning in Britain demonstrates the potential for mass accidental poisoning. It emphasises the need for strict public health controls and the importance of good liaison between emergency services to ensure that such events are quickly recognised and that the necessary resources are organised.

Carbon Monoxide Poisoning Sir

Sir, The recent review of carbon monoxide poisoning by Balzan et al' provided helpful advice about this sometimes difficult diagnosis. We would, however, hesitate to follow the recommendations made about the treatment of CO poisoning. Their assessment of the benefit of hyperbaric oxygen (HBO) does not appear to be based on the presented evidence and the potential complications of transporting c...

Ethylene glycol poisoning and lactate concentrations.

We were interested to read the article by Manini et al. (1), which confirmed previous observations that a severe ethylene glycol poisoning may lead to falsely elevated lactate levels (2). High lactate levels were indeed measured by enzymatic spectrophotometry (Integra analyzer) but excluded by a specific GC analysis. A linear correlation was nicely demonstrated between the serially determined b...